Comparative and Functional Genomics
2004

A critical view of yeast interactome and gonad transcriptomes in zebrafish

publication

Author Information

Author(s): Michael Cornell, Yang Li, Dawn Jones, Yang Xie

Conclusion

The study identifies genes with organ-specific expression patterns in zebrafish gonads and profiles the heat shock response in yeast mutants.

Supporting Evidence

  • Researchers constructed cDNA libraries from adult zebrafish testis and ovary.
  • Microarrays were used to identify genes with organ-specific expression patterns.
  • Loss of the PDE2 gene in yeast leads to reduced stress tolerance.

Takeaway

Researchers looked at how genes work in zebrafish and yeast, finding important information about how these organisms respond to stress and how their genes are expressed in different organs.

Methodology

Microarrays were used to profile gene expression in zebrafish and yeast.

Digital Object Identifier (DOI)

10.1002/cfg.417

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