Diagnosis Osteoporosis Risk: Using Machine Learning Algorithms Among Fasa Adults Cohort Study (FACS)
2025

Using Machine Learning to Diagnose Osteoporosis Risk in Adults

Sample size: 10108 publication 10 minutes Evidence: high

Author Information

Author(s): Tabib Saghar, Alizadeh Seyed Danial, Andishgar Aref, Pezeshki Babak, Keshavarzian Omid, Tabrizi Reza

Primary Institution: Fasa University of Medical Sciences

Hypothesis

Can machine learning techniques accurately identify osteoporosis risk factors in the Fasa Adults Cohort Study?

Conclusion

The XGB model had the best performance in assessing the risk of osteoporosis in the Iranian population.

Supporting Evidence

  • The XGB model achieved an AUC of 0.78, indicating good performance.
  • Age, calcium intake, and red blood cell count were identified as key risk factors.
  • The study included a large sample size of over 10,000 participants.
  • Machine learning methods showed potential for early detection of osteoporosis.
  • Traditional diagnostic tools are often impractical in developing countries.

Takeaway

Researchers used computers to help find out who might have osteoporosis, a disease that makes bones weak. They found that a special computer method worked best for this.

Methodology

The study analyzed data from the Fasa Adults Cohort Study using eight machine learning methods to evaluate osteoporosis risk.

Potential Biases

Self-reported data may lead to underestimation of osteoporosis prevalence.

Limitations

The study relied on self-reported data, which may introduce errors and affect the accuracy of results.

Participant Demographics

Participants included 10,108 individuals aged 35 to 70, with a male-to-female ratio of 0.8:1.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 0.74–0.82

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/edm2.70023

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