Triglyceride-Glucose Index and Hypertension Risk in Older Chinese Adults
Author Information
Author(s): Zheng Huoping, Xu Meiling, Yang Jing, Xu Mingjun
Primary Institution: Department of Endocrinology and Metabolism, The Third People’s Hospital of Jingdezhen, Jingdezhen, China
Hypothesis
This study aimed to explore the association between the triglyceride-Glucose Index (TyG) and its combination with obesity indicators in relation to the risk of hypertension among middle-aged and elderly individuals in China.
Conclusion
As the levels of TyG, TyG-BMI, TyG-WC, and TyG-WHtR increased, the risk of hypertension among middle-aged and elderly individuals aged 45 and above in China rises significantly.
Supporting Evidence
- The prevalence of hypertension increased across quartiles of TyG, TyG-BMI, TyG-WC, and TyG-WHtR.
- Odds ratios for hypertension risk increased significantly with higher quartiles of TyG and its combined indicators.
- TyG-WC showed the highest diagnostic performance for hypertension with an AUC of 0.642.
Takeaway
This study found that higher levels of certain fat and sugar indicators can increase the chances of having high blood pressure in older people.
Methodology
The study analyzed data from 9,248 participants aged 45 and above, using logistic regression to evaluate the association between TyG indices and obesity indicators with hypertension risk.
Limitations
The study's cross-sectional design limits causal inferences, and there may be unexamined confounding variables.
Participant Demographics
Participants were middle-aged and elderly individuals aged 45 and above, with an average age of 61.38 years, including 46.21% males.
Statistical Information
P-Value
p<0.001
Confidence Interval
95% CI: 1.48–2.19
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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