Emerging Resistance of Salmonella Enteritidis in Trinidad and Tobago
Author Information
Author(s): B.P. Cherian, Nicole Singh, W. Charles, P. Prabhakar
Primary Institution: Port of Spain General Hospital, Port of Spain, Trinidad; and Caribbean Epidemiology Center (CAREC), Port of Spain, Trinidad
Hypothesis
What is the mechanism behind the third-generation cephalosporin resistance in Salmonella Enteritidis?
Conclusion
This study reports the first case of Salmonella Enteritidis resistant to third-generation cephalosporins in the Caribbean.
Supporting Evidence
- S. Enteritidis caused 79 (66%) of 119 culture-confirmed salmonella infections in Trinidad in 1997.
- None of the 216 isolates tested were resistant to cephalosporins, aminoglycosides, ampicillin, trimethoprim-sulphamethoxazole, chloramphenicol, and norfloxacin/ciprofloxacin.
- This isolate was sensitive only to ofloxacin and imipenem.
Takeaway
Some germs that make people sick can become strong and not get killed by medicines. This study found one of those strong germs in a sick person in Trinidad.
Methodology
The study tested 216 human Salmonella Enteritidis isolates for antimicrobial susceptibility using the Kirby-Bauer disk diffusion method.
Limitations
The study is limited to a specific geographic area and may not represent global trends.
Participant Demographics
The patient was a febrile, nonneutropenic individual with multiple myeloma.
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