Emblica Officinalis: A Novel Therapy for Acute Pancreatitis
Author Information
Author(s): S. P. Thorat, N. N. Rege, A. S. Naik, U. M. Thatte, A. Joshi, K. N. S. Panicker, R. D. Bapat, S. A. Dahanukar
Primary Institution: Seth G. S. Medical College and K. E. M. Hospital
Hypothesis
This study was carried out to evaluate the protective effect of Emblica officinalis against acute necrotising pancreatitis in dogs.
Conclusion
Pretreatment with Emblica officinalis prevents acute necrotising pancreatitis in dogs.
Supporting Evidence
- Serum amylase increased significantly in the control group after inducing pancreatitis.
- The rise in serum amylase in the E.o. treated group was not statistically significant.
- Light microscopic examination showed less acinar cell damage in the E.o. treated group.
- Electron microscopy confirmed increased smooth endoplasmic reticulum in E.o. treated cells.
Takeaway
The study tested a plant called Emblica officinalis to see if it could help dogs with a serious stomach problem called pancreatitis, and it found that it did help.
Methodology
Twenty-eight dogs were divided into four groups, with one group receiving pretreatment with Emblica officinalis before inducing pancreatitis.
Limitations
Further studies are needed to explore the clinical potential of E.o. and its mechanism of action.
Participant Demographics
Mongrel dogs of either sex.
Statistical Information
P-Value
p<0.02
Statistical Significance
p<0.05
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