Dynamics of Airborne Influenza A Viruses Indoors and Dependence on Humidity
2011

How Humidity Affects Airborne Influenza A Viruses

publication 10 minutes Evidence: moderate

Author Information

Author(s): Yang Wan, Linsey C. Marr, Ron A. M. Fouchier

Primary Institution: Virginia Tech

Hypothesis

Airborne concentrations of infectious influenza A viruses (IAVs) vary with humidity through its influence on virus inactivation rate and respiratory droplet size.

Conclusion

Higher humidity levels reduce the concentration of infectious IAVs in the air, which may help lower the risk of influenza transmission.

Supporting Evidence

  • The predicted concentration of infectious IAVs in air is 2.4 times higher at 10% RH than at 90% RH after 10 minutes.
  • Settling is important for removal of large droplets containing large amounts of IAVs.
  • The inactivation rate increases linearly with RH; at the highest RH, inactivation can remove up to 28% of IAVs in 10 minutes.

Takeaway

When the air is more humid, the tiny droplets that carry the flu virus shrink less and fall to the ground faster, making it harder for the virus to spread.

Methodology

The study modeled the size distribution and dynamics of IAVs emitted from a cough in various humidity levels, analyzing factors like droplet size transformation and virus inactivation.

Limitations

The model is based on limited laboratory data and does not account for all factors affecting virus transmission in real-world settings.

Statistical Information

P-Value

0.0015

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pone.0021481

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