Causes and Outcomes of Acute Kidney Injury in Sri Lanka
Author Information
Author(s): Herath Nalaka, De Silva Shamila, Liyanage Prasitha, Kumara Sameera, Devi Suganthika, Abeysekara Vajira, Mallawarachi Ruvini, Perera Suharshi, Karunathilaka Iresha, Samarasinghe Sameera, Weerakoon Kosala
Primary Institution: Colombo North Teaching Hospital, Ragama, Sri Lanka
Hypothesis
The outcome of acute kidney injury (AKI) depends on causes, patient factors, and care received.
Conclusion
AKI in elderly and comorbid patients has high morbidity and mortality.
Supporting Evidence
- Of the 464 patients studied, 262 (56.5%) were males.
- 212 patients (45.69%) were discharged with normal renal function.
- Mortality was low in patients with prerenal causes of AKI.
- Progression of AKI to chronic kidney disease or death was significantly high in patients aged > 60 years.
Takeaway
This study looked at why people get sick kidneys and what happens to them afterward. It found that older people and those with other health problems are more likely to get really sick or die from kidney issues.
Methodology
This retrospective study analyzed patients aged 18 years or older with AKI referred to nephrology services over 15 months, using hospital records.
Potential Biases
Potential bias due to retrospective design and incomplete data.
Limitations
Lack of completeness of medical records and loss to follow-up at 3 months.
Participant Demographics
The mean age of participants was 57.04 years, with 56.5% being male.
Statistical Information
P-Value
p=0.017
Confidence Interval
95% CI: 0.35–0.99
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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