Zoonotic Transmission of Simian Foamy Viruses in Asia
Author Information
Author(s): Jones-Engel Lisa, May Cynthia C., Engel Gregory A., Steinkraus Katherine A., Schillaci Michael A., Fuentes Agustin, Rompis Aida, Chalise Mukesh K., Aggimarangsee Nantiya, Feeroz Mohammed M., Grant Richard, Allan Jonathan S., Putra Arta, Wandia I. Nengah, Watanabe Robin, Kuller LaRene, Thongsawat Satawat, Chaiwarith Romanee, Kyes Randall C., Linial Maxine L.
Primary Institution: University of Washington
Hypothesis
What is the prevalence of simian foamy virus (SFV) infection among humans living or working near nonhuman primates in Asia?
Conclusion
SFV infections are likely prevalent among persons who live or work near nonhuman primates in Asia, with a confirmed prevalence of 2.6%.
Supporting Evidence
- 8 out of 305 tested individuals were confirmed SFV positive.
- 5 macaque taxa were implicated as potential sources of infection.
- SFV prevalence in at-risk populations was previously reported as 1%-6%.
Takeaway
People who live or work close to monkeys in Asia can get a virus from them, and this study found that about 3 out of every 100 people tested had the virus.
Methodology
The study tested 305 individuals from various countries in Asia for SFV infection using serological assays and phylogenetic analysis.
Potential Biases
Potential bias in self-reported exposure data and the limited demographic diversity of the sample.
Limitations
The study may not capture all potential cases of SFV infection due to the limited sample size and specific geographic focus.
Participant Demographics
Participants included 172 men and 133 women, aged 18 to 80, from Thailand, Indonesia, Nepal, and Bangladesh.
Statistical Information
P-Value
0.009
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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