How are the cellular functions of myosin VI regulated within the cell?
2007

Understanding Myosin VI: Functions and Regulation

publication Evidence: moderate

Author Information

Author(s): Folma Buss, John Kendrick-Jones

Primary Institution: University of Cambridge

Hypothesis

How are the cellular functions of myosin VI regulated within the cell?

Conclusion

Myosin VI plays crucial roles in various cellular processes and is regulated by multiple mechanisms.

Supporting Evidence

  • Myosin VI is involved in endocytosis, exocytosis, and cell migration.
  • It is the only myosin that moves towards the minus end of actin filaments.
  • Myosin VI's functions are regulated by calcium ions, phosphorylation, and binding to specific proteins.

Takeaway

Myosin VI is a special protein that helps cells move and communicate, and it works in different ways depending on the situation.

Digital Object Identifier (DOI)

10.1016/j.bbrc.2007.11.150

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