Accuracy of Prenatal Diagnosis in Elective Termination of Pregnancy
Author Information
Author(s): Fabiana Ramos, Sofia Maia, Miguel Branco, Joana Raposo, Joaquim Sá, Sérgio Sousa, Margarida Venâncio, Raquel Pina, Eulália Galhano, Lina Ramos, Jorge Saraiva
Primary Institution: Centro Hospitalar de Coimbra
Hypothesis
To evaluate the quality of prenatal results in all cases of termination of pregnancy due to fetal abnormalities.
Conclusion
The study found that chromosome abnormalities were the most common reason for termination of pregnancy, and the involvement of a multidisciplinary team significantly improved genetic counseling.
Supporting Evidence
- Chromosome abnormalities were found in 39% of cases.
- Total agreement between ultrasound and genetic findings was only 37%.
- Genetic evaluation changed the etiological diagnosis in 21% of cases.
Takeaway
This study looked at 385 cases where pregnancies were ended because of problems with the baby. It found that doctors can get better information about these problems by working together.
Methodology
Retrospective analysis of 385 cases of termination of pregnancy due to fetal abnormalities, comparing ultrasound, genetic, and postmortem findings.
Limitations
The study is limited to a single center and may not represent broader populations.
Participant Demographics
The study involved cases from a tertiary prenatal diagnosis center in Coimbra, Portugal.
Digital Object Identifier (DOI)
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