Antigenotoxic Studies of Substances to Reduce DNA Damage from Aflatoxin B1 and Ochratoxin A
Author Information
Author(s): Madrigal-Santillán Eduardo, Morales-González José A., Vargas-Mendoza Nancy, Reyes-Ramírez Patricia, Cruz-Jaime Sandra, Sumaya-Martínez Teresa, Pérez-Pastén Ricardo, Madrigal-Bujaidar Eduardo
Primary Institution: Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo
Hypothesis
Can certain substances reduce the DNA damage caused by aflatoxin B1 and ochratoxin A?
Conclusion
The study suggests that various substances can help reduce the toxic effects of aflatoxin B1 and ochratoxin A in animals.
Supporting Evidence
- AFB1 is a potent natural mutagen and carcinogen.
- Antimutagenic agents can inhibit the interaction of mycotoxins with DNA.
- Different strategies have been developed to reduce mycotoxin exposure.
Takeaway
Some foods can be harmful because they contain toxins from mold, but certain substances can help protect against these toxins.
Methodology
The review summarizes various strategies and substances tested for their ability to reduce DNA damage caused by mycotoxins.
Limitations
The effectiveness of some methods may alter the nutritional value of food.
Digital Object Identifier (DOI)
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