Association of binge alcohol use with functional outcomes among individuals with COVID-19 infection
2025

Binge Alcohol Use and Functional Outcomes in COVID-19 Patients

Sample size: 3529 publication 10 minutes Evidence: moderate

Author Information

Author(s): Tong Sebastian T, Gottlieb Michael, Ebna Mannan Imtiaz, Zheng Zihan, Sinha Manisha, Santangelo Michelle, Gatling Kristyn, Kean Efrat, Watts Phillip, Wang Ralph, Montoy Juan Carlos, Idris Ahamed, MacDonald Samuel, Huebinger Ryan, Hill Mandy, O’Laughlin Kelli N, Gentile Nicole L, Dorney Jocelyn, Malicki Caitlin, Elmore Joann G, Diaz Roldan Kate, Chan Gary, Lin Zhenqiu, Weinstein Robert A, Stephens Kari A

Primary Institution: University of Washington

Hypothesis

Is there an association between binge alcohol use and long-term functional outcomes among individuals with COVID-19 infection?

Conclusion

Binge alcohol use before COVID-19 infection was associated with statistically significant but clinically irrelevant improvements in function at three months, which were not sustained at six months.

Supporting Evidence

  • 23.7% of individuals screened positive for binge drinking.
  • At three months, binge drinkers reported better physical function and less pain interference.
  • No significant associations were found at six months.
  • Postinfectious and pandemic stressors may have impacted functional outcomes more than binge alcohol use.
  • Demographic factors such as age, gender, and education were associated with binge drinking prevalence.

Takeaway

People who drank a lot of alcohol before getting COVID-19 seemed to feel a little better physically three months later, but this didn't last for six months.

Methodology

A prospective, longitudinal, multisite cohort study design was used to evaluate the association between binge alcohol use and functional outcomes using PROMIS-29 scores three and six months postinfection.

Potential Biases

Potential underreporting of binge drinking and lack of control for nonbinge alcohol use.

Limitations

Underreporting of binge alcohol use is common; nonbinge alcohol use was not captured; alcohol use was only assessed at baseline.

Participant Demographics

The cohort included 23.7% binge drinkers, with a higher prevalence among younger ages, males, and those with higher education.

Statistical Information

P-Value

p<0.05

Confidence Interval

[0.44, 1.71]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1093/alcalc/agae086

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