Antimicrobial activities of pomegranate rind extracts: enhancement by addition of metal salts and vitamin C
2008

Antimicrobial Activities of Pomegranate Rind Extracts

publication Evidence: moderate

Author Information

Author(s): McCarrell Erin M, Gould Simon WJ, Fielder Mark D, Kelly Alison F, El Sankary Waffa, Naughton Declan P

Primary Institution: School of Life Sciences, Kingston University, Kingston-upon-Thames, UK

Hypothesis

The study aims to determine the antimicrobial activities of combinations of pomegranate rind extracts with metal salts and vitamin C.

Conclusion

The study demonstrates that combinations of pomegranate rind extracts with metal salts and vitamin C enhance antimicrobial efficacy against certain bacteria.

Supporting Evidence

  • Pomegranate rind extracts showed activity against Gram positive bacteria after 24 hours.
  • Addition of Cu (II) salts to pomegranate rind extracts extended antimicrobial activity against E. coli, Ps. aeruginosa, and P. mirabilis.
  • Vitamin C significantly enhanced the antimicrobial activities of pomegranate rind extracts combined with metal salts.

Takeaway

Pomegranate rind extracts can fight germs better when mixed with certain metals and vitamin C.

Methodology

The study used disc diffusion and suspension assays to test the antimicrobial activities of pomegranate rind extracts alone and in combination with metal salts and vitamin C.

Limitations

The study primarily focused on short-term exposure and did not explore long-term stability or effects.

Statistical Information

P-Value

p < 0.001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1472-6882-8-64

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