Metabolic and endocrine profiles and reproductive parameters in dairy cows under grazing conditions: effect of polymorphisms in somatotropic axis genes
2011

Effects of Gene Variations on Dairy Cows' Health and Milk Production

Sample size: 186 publication 10 minutes Evidence: moderate

Author Information

Author(s): Ruprechter Gretel, Carriquiry Mariana, Ramos Juan Manuel, Pereira Isabel, Ana Meikle

Primary Institution: Faculty of Veterinary Medicine and Agronomy Sciences, University of Uruguay

Hypothesis

GH-AluI and IGF-I-SnabI polymorphisms do change the metabolic/endocrine profiles in Holstein cows during the transition period, which in turn are associated with productive and reproductive parameters.

Conclusion

The GH and IGF-I genotypes had no substantial effect on productive parameters, although IGF-I genotype affected calving-first service interval in primiparous cows.

Supporting Evidence

  • GH genotype did not affect productive variables in either farm.
  • IGF-I genotype affected calving-first service interval in primiparous cows.
  • LL cows had lower NEFA and greater IGF-I concentrations than LV cows.

Takeaway

This study looked at how certain genes in dairy cows affect their health and milk production. It found that while these genes don't change how much milk they produce, they can affect how quickly they can breed again after having a calf.

Methodology

Holstein cows from two farms were genotyped for GH and IGF-I, and blood samples were analyzed for metabolic and endocrine parameters during the transition period.

Potential Biases

Potential bias due to the small sample size of certain genotypes and the specific grazing conditions of the farms.

Limitations

The study was limited by the unequal distribution of GH genotypes and the focus on only two farms.

Participant Demographics

Primiparous and multiparous Holstein cows from two commercial dairy herds in Uruguay.

Statistical Information

P-Value

0.07

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1751-0147-53-35

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