Malignant Struma Ovarii: Treatment and Outcomes
Author Information
Author(s): Janszen Erica W.M., van Doorn Helena C., Ewing Patricia C., de Krijger Ronald R., de Wilt Johannes H.W., Kam Boen L.R., de Herder Wouter W.
Primary Institution: Erasmus Medical Center
Hypothesis
What is the best treatment approach for malignant struma ovarii?
Conclusion
Surgical removal of the ovarian lesion followed by total thyroidectomy and radioiodine ablation therapy is the best treatment for malignant struma ovarii.
Supporting Evidence
- All three patients underwent surgery followed by thyroidectomy and radioiodine therapy.
- Two patients had stable disease after treatment for four years.
- Histological diagnosis showed similarities to well differentiated thyroid carcinoma.
Takeaway
Malignant struma ovarii is a rare type of tumor in the ovary, and the best way to treat it is by removing the tumor and the thyroid gland, then using a special treatment to kill any remaining cancer cells.
Methodology
Case reports of three patients treated with surgery, thyroidectomy, and radioiodine ablation therapy.
Limitations
The rarity of the condition limits the generalizability of the findings.
Participant Demographics
Three female patients aged 32 to 52 years.
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