AI predictive models and advancements in microdissection testicular sperm extraction for non-obstructive azoospermia: a systematic scoping review
2024

AI Models and Testicular Sperm Extraction for Male Infertility

Sample size: 11636 publication Evidence: moderate

Author Information

Author(s): Hossein Jamalirad, Mahdie Jajroudi, Bahareh Khajehpour, Mohammad Ali Sadighi Gilani, Saeid Eslami, Marjan Sabbaghian, Hassan Vakili Arki

Primary Institution: Mashhad University of Medical Sciences, Mashhad, Iran

Hypothesis

How accurately can artificial intelligence (AI) models predict sperm retrieval in non-obstructive azoospermia (NOA) patients undergoing micro-testicular sperm extraction (m-TESE) surgery?

Conclusion

AI predictive models hold significant promise in predicting successful sperm retrieval in NOA patients undergoing m-TESE, although limitations regarding variability of study designs, small sample sizes, and a lack of validation studies restrict the overall generalizability of studies in this area.

Supporting Evidence

  • AI models can analyze various factors to predict sperm retrieval success.
  • Machine learning techniques have shown promise in improving predictions for sperm retrieval.
  • Limitations in current studies include small sample sizes and lack of validation.

Takeaway

Doctors can use AI to help predict if a man with a specific type of infertility will be able to get sperm from his testicles for having a baby. This can help them make better decisions about treatment.

Methodology

A systematic scoping review was conducted following PRISMA-ScR guidelines, covering PubMed and Scopus databases from 2013 to May 2024, including studies on patients with NOA where AI-based models were used for predicting m-TESE outcomes.

Potential Biases

All included studies demonstrated a low risk of bias and minimal concerns regarding applicability.

Limitations

The review includes heterogeneity of included research, potential publication bias, reliance on only two databases, and absence of a meta-analysis.

Participant Demographics

The review covered information from 11,636 patients with NOA who had undergone m-TESE.

Digital Object Identifier (DOI)

10.1093/hropen/hoae070

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