Pilot Study to Evaluate the Appropriate Management of Patients With Coexistent Bacterial Vaginosis and Cervicitis
1995

Managing Bacterial Vaginosis and Cervicitis

Sample size: 31 publication Evidence: moderate

Author Information

Author(s): Jane R. Schwebke, Mary Beth Schulien, Mark Zajackowski

Primary Institution: Chicago Department of Health and Northwestern University Medical School

Hypothesis

Does treating cervicitis alone resolve bacterial vaginosis in women?

Conclusion

Simultaneous treatment of bacterial vaginosis and cervicitis is necessary to effectively eradicate bacterial vaginosis.

Supporting Evidence

  • 95% of women treated with doxycycline alone had persistent bacterial vaginosis.
  • Only 14% of women treated with doxycycline and metronidazole had persistent bacterial vaginosis.
  • The study suggests that treating both conditions is necessary for effective management.

Takeaway

If a woman has both bacterial vaginosis and cervicitis, treating both is important to get rid of the infection.

Methodology

Women with bacterial vaginosis and cervicitis were treated with doxycycline alone or doxycycline plus metronidazole, and outcomes were assessed after 3-4 weeks.

Potential Biases

Potential bias due to noncompliance and lack of blinding.

Limitations

The study had a small sample size and was conducted in a single clinic.

Participant Demographics

All participants were women attending an inner-city STD clinic, predominantly African American.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

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