Antimicrobial Activities of Artocarpus communis
Author Information
Author(s): Kuete Victor, Ango Patrick Y, Fotso Ghislain W, Kapche Gilbert DWF, Dzoyem Jean P, Wouking Arlette G, Ngadjui Bonaventure T, Abegaz Berhanu M
Primary Institution: Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
Hypothesis
This work was designed to investigate the antimicrobial activities of the methanol extract and compounds isolated from the bark of Artocarpus communis.
Conclusion
The study provides supportive data for the use of A. communis and some of its constituents for treating infections associated with the studied microorganisms.
Supporting Evidence
- The methanol extract and compounds from A. communis inhibited the growth of all tested microbial species.
- The lowest MIC value of 64 μg/ml was recorded on Staphylococcus aureus and Escherichia coli.
- Compounds 4 and 5 showed significant antimicrobial activity against Pseudomonas aeruginosa.
Takeaway
Researchers found that a plant called Artocarpus communis can help fight germs that make people sick.
Methodology
The liquid microdilution assay was used to determine the minimal inhibitory concentration (MIC) and minimal microbicidal concentration (MMC) against various bacterial and fungal species.
Limitations
The study's findings need further confirmation through pharmacological and toxicological studies.
Digital Object Identifier (DOI)
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