Velocities of Bone Mineral Accrual in Black and White American Children
2010

Bone Mineral Growth in Black and White Children

Sample size: 188 publication 10 minutes Evidence: moderate

Author Information

Author(s): Hui Siu L, Perkins Anthony J, Harezlak Jaroslaw, Peacock Munro, McClintock Cindy L, Johnston C Conrad

Primary Institution: Indiana University School of Medicine

Hypothesis

Black children gain bone mineral faster than white children during puberty.

Conclusion

The higher bone mass in black adults compared to whites is due to faster bone mineral accrual in prepuberty, not during puberty.

Supporting Evidence

  • Black children had higher total-body bone mineral content than white children at all ages.
  • Black children entered puberty earlier but spent only slightly longer in puberty than white children.
  • Most racial differences in bone mineral accrual can be explained by growth in size.

Takeaway

Black children grow their bones faster than white children before puberty, but during puberty, white children grow faster.

Methodology

A cohort study measuring total-body bone mineral content in 188 children over 4 years.

Potential Biases

Potential bias due to self-reported Tanner stages and unequal age distributions.

Limitations

The study was limited by the age range of subjects and moderate sample size.

Participant Demographics

188 healthy children aged 5 to 15, with 91 males and 97 females, balanced between black and white.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/jbmr.43

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