Epidemiology of acute and chronic hepatitis B virus infection in Norway, 1992-2009
2011

Hepatitis B Infection in Norway: 1992-2009

Sample size: 9800 publication 10 minutes Evidence: moderate

Author Information

Author(s): Rimšelienė Gražina, Nilsen Øivind, Kløvstad Hilde, Blystad Hans, Aavitsland Preben

Primary Institution: Norwegian Institute of Public Health

Hypothesis

To assess the validity of current risk groups for hepatitis B in Norway and recommend preventive measures.

Conclusion

IDUs remain the largest risk group for acute hepatitis B, and increased immigration from high endemic countries is linked to peaks in chronic hepatitis B cases.

Supporting Evidence

  • The annual incidence of acute hepatitis B ranged from 0.7 to 10.6 per 100,000.
  • 64% of acute hepatitis B cases were among IDUs.
  • Chronic hepatitis B was more likely to be diagnosed among immigrants than Norwegians.
  • The risk of acquiring acute hepatitis B was highest in people aged 20-29.
  • There were two peaks of chronic hepatitis B cases in 2003 and 2009.

Takeaway

This study looked at hepatitis B cases in Norway over 17 years and found that drug users are the most affected group, while immigrants from countries with high hepatitis B rates are also at risk.

Methodology

Data was collected from the national surveillance system for hepatitis B, analyzing reported cases by year, sex, age, and geographical location.

Potential Biases

Potential bias due to incomplete data on sexual orientation and exposure routes.

Limitations

Data on exposure was unknown for 83% of chronic hepatitis B cases, and there was under-reporting of acute cases.

Participant Demographics

The study included cases from various demographics, with a focus on IDUs and immigrants.

Statistical Information

Confidence Interval

95%

Digital Object Identifier (DOI)

10.1186/1471-2334-11-153

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