Increasing thyroid cancer incidence in Canada, 1970–1996: time trends and age-period-cohort effects
2001
Thyroid Cancer Incidence Trends in Canada
publication
Author Information
Author(s): Liu S, Semenciw R, Ugnat A-M, Mao Y
Primary Institution: Health Surveillance and Epidemiology Division, Centre for Healthy Human Development, Health Canada, Ottawa
Hypothesis
What are the time trends and effects of age, period, and cohort on thyroid cancer incidence in Canada from 1970 to 1996?
Conclusion
Thyroid cancer incidence in Canada doubled from 1970 to 1996, primarily due to papillary carcinoma.
Supporting Evidence
- Thyroid cancer incidence rates doubled from 3.3 per 100,000 in 1970-72 to 6.8 per 100,000 in 1994-96 for females.
- For males, the rates increased from 1.1 per 100,000 to 2.2 per 100,000 in the same period.
- The increase was largely attributed to papillary carcinoma of the thyroid.
- Age, birth cohort, and period effects were significant for females, while age and birth cohort effects were significant for males.
- There were notable differences in trends between genders.
Takeaway
More people in Canada are being diagnosed with thyroid cancer now than in the past, especially a specific type called papillary carcinoma.
Methodology
Age-specific incidence rates were calculated and age-period-cohort modeling was used to estimate effects.
Digital Object Identifier (DOI)
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