Urinary Silicon Excretion in Relation to Lactation and Bone Mineral Density — a Longitudinal Study Post-partum
2025

Silicon Excretion During Lactation and Bone Health

Sample size: 81 publication 10 minutes Evidence: moderate

Author Information

Author(s): Catarina Magnusson, Hanna Augustin, Ravin Jugdaohsingh, Jonathan J. Powell, Lena Hulthén, Maria Ransjö

Primary Institution: University of Gothenburg

Hypothesis

Does urinary silicon excretion change during lactation and relate to bone mineral density?

Conclusion

Women lactating for 4 months or longer have higher urinary silicon concentrations post-partum, but these changes are not linked to changes in bone mineral density.

Supporting Evidence

  • Women lactating for 4–8.9 months had significantly higher urinary silicon at 4 months post-partum compared to the third trimester.
  • No significant longitudinal differences in urinary silicon were found after correcting for creatinine.
  • Changes in urinary silicon and bone mineral density were not correlated, except at the lumbar spine for a specific lactation duration.

Takeaway

This study looked at how much silicon new mothers pee out and if it affects their bones. It found that moms who breastfeed longer might pee out more silicon, but it doesn't seem to help their bones get stronger.

Methodology

The study collected urine samples from pregnant women at various post-partum intervals and measured urinary silicon and calcium levels, along with bone mineral density.

Potential Biases

Potential biases related to self-reported health status and dietary intake were not controlled for.

Limitations

The study used spot urine samples instead of 24-hour collections, which may affect the accuracy of the results.

Participant Demographics

Participants were 81 pregnant women aged 25-40, recruited from maternal healthcare centers in South Western Sweden.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1007/s12011-024-04175-8

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