Acetobacter indonesiensis Pneumonia after Lung Transplant
Author Information
Author(s): Bittar Fadi, Reynaud-Gaubert Martine, Thomas Pascal, Boniface Stéphanie, Raoult Didier, Rolain Jean-Marc
Primary Institution: Unité de Research sur les Maladies Infectieuses et Tropicales Emergentes, Marseille, France
Hypothesis
Is Acetobacter indonesiensis an emerging opportunistic pathogen in immunocompromised patients?
Conclusion
The study suggests that Acetobacter indonesiensis may be an emerging opportunistic pathogen in immunocompromised patients, particularly those with cystic fibrosis who have undergone lung transplantation.
Supporting Evidence
- The patient was chronically colonized by multiple resistant bacteria before the transplant.
- Acetobacter indonesiensis was identified after partial sequencing of the 16S rRNA gene.
- The bacterium was multiresistant to antimicrobial agents, including colistin.
- The patient improved after an adapted antimicrobial drug therapy.
Takeaway
A patient with cystic fibrosis got a lung transplant and developed a rare infection from a bacteria called Acetobacter indonesiensis, which is usually found in fruits and flowers. After changing his medicine, he got better.
Methodology
The identification of the bacterium was achieved through partial sequencing of the 16S rRNA gene and antimicrobial susceptibility testing using the Vitek 2 Auto system.
Limitations
The source of contamination for the patient remains unknown, and the study is based on a single case.
Participant Demographics
A 31-year-old man with cystic fibrosis.
Digital Object Identifier (DOI)
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