Anaphylactic reaction to intravenous diclofenac
2011
Anaphylactic Reaction to Intravenous Diclofenac
publication
Evidence: low
Author Information
Author(s): Ranju Singh, Deepak Baduni, Neha Vajifdar, Homay
Primary Institution: Lady Hardinge Medical College & Associated Hospitals
Hypothesis
Can intravenous diclofenac sodium cause anaphylactic reactions?
Conclusion
Intravenous diclofenac can cause severe anaphylactic reactions that may mimic pulmonary embolism.
Supporting Evidence
- Anaphylaxis due to intravenous diclofenac sodium is very rare.
- The clinical features of the anaphylactic reaction mimicked pulmonary embolism.
- Serum tryptase levels were elevated, indicating anaphylactic reaction.
- CT pulmonary angiography showed no evidence of pulmonary embolism.
Takeaway
Sometimes, a medicine called diclofenac can make people very sick, even though it's usually safe. This can look like other problems, like a blood clot in the lungs.
Methodology
Case report of a 25-year-old female experiencing anaphylaxis after IV diclofenac administration.
Limitations
The patient did not return for skin prick testing to confirm the diagnosis.
Participant Demographics
25-year-old primigravida female.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website