Reproductive factors and oesophageal cancer in Chinese women: a case-control study
2011

Reproductive Factors and Oesophageal Cancer in Chinese Women

Sample size: 230 publication 10 minutes Evidence: moderate

Author Information

Author(s): Chen Zu-Hui, Shao Jian-Li, Lin Jin-Rong, Zhang Xia, Chen Qing

Primary Institution: College of Clinical Medicine, Jinan University

Hypothesis

Does giving birth at a later age increase the risk of oesophageal cancer in Chinese women?

Conclusion

Giving birth at a later age may increase the risk of oesophageal cancer in women.

Supporting Evidence

  • Women who had given birth before were not at increased risk compared to childless women.
  • The risk of oesophageal cancer increased with age at first birth.
  • History of spontaneous abortion was not significantly associated with increased risk.

Takeaway

Having babies later in life might make women more likely to get oesophageal cancer.

Methodology

A case-control study with face-to-face interviews conducted on 73 cases and 157 controls.

Potential Biases

There is a risk of selection bias as controls were not randomly selected from the general population.

Limitations

The study had a limited number of cases, which may affect statistical power.

Participant Demographics

Participants were Chinese females with newly diagnosed primary oesophageal cancer and controls without cancer.

Statistical Information

P-Value

0.047

Confidence Interval

95% CI: 1.01 ~ 4.04

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-230X-11-49

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