Bibliometric and visual analysis of human microbiome—breast cancer interactions: current insights and future directions
2024

Analyzing the Relationship Between the Microbiome and Breast Cancer

Sample size: 736 publication 10 minutes Evidence: moderate

Author Information

Author(s): Zhou Yi, Jiang Min, Li Xiaoyu, Shen Ke, Zong Hui, Lv Qing, Shen Bairong

Primary Institution: West China Hospital, Sichuan University, Sichuan, China

Hypothesis

What is the impact of the human microbiome on breast cancer development and treatment?

Conclusion

The study reveals a growing body of research indicating that the gut microbiome composition is linked to breast cancer progression and treatment outcomes.

Supporting Evidence

  • Research shows that the gut microbiome differs between breast cancer patients and healthy individuals.
  • Animal studies indicate that changes in gut microbiome can influence breast tumor growth.
  • Keyword analysis highlights a shift towards anti-tumor therapies and personalized medicine in current research.

Takeaway

This study looks at how tiny germs in our bodies might affect breast cancer, showing that they can change how the disease develops and how well treatments work.

Methodology

The study conducted a bibliometric analysis of 736 publications from the Web of Science Core Collection, focusing on trends and contributions in microbiome and breast cancer research.

Potential Biases

The study may be biased towards English-language publications and those indexed in the WoSCC.

Limitations

The analysis is limited to publications in the WoSCC, potentially excluding relevant studies from other databases and non-English publications.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.3389/fmicb.2024.1490007

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