Premature Constriction of Fetal Ductus Arteriosus Caused by Sertraline in a Pregnant Woman
Author Information
Author(s): Alireza Golbabaei, Elham sadat Alavi moghaddam, Hooman Mohammad Talebi
Primary Institution: Tehran University of Medical Sciences
Hypothesis
Is there an association between sertraline use during pregnancy and premature constriction of the ductus arteriosus?
Conclusion
The case highlights the association between sertraline and premature ductus arteriosus constriction, suggesting the need for careful evaluation of medication use during pregnancy.
Supporting Evidence
- Sertraline has been shown to have a vasoconstriction effect on the ductus arteriosus in animal studies.
- Human studies indicate that SSRIs prescription during pregnancy can cause cardiovascular disorders.
- The pregnancy continued without a cesarean, indicating potential for normal delivery despite the condition.
Takeaway
A pregnant woman took a medicine called sertraline, which caused a problem with her baby's heart vessel, but stopping the medicine helped fix it.
Methodology
Fetal echocardiography was performed, and the patient's medication was changed after psychiatric consultation.
Potential Biases
Potential bias in reporting due to the nature of a case report.
Limitations
The study is based on a single case report, limiting generalizability.
Participant Demographics
39-year-old pregnant woman, 2 pregnancies, 1 abortion, 0 living children.
Digital Object Identifier (DOI)
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