Immunohistochemical localization of CD1a-positive putative dendritic cells in human breast tumours
1999
Study of CD1a-positive Cells in Breast Tumors
Sample size: 52
publication
Evidence: moderate
Author Information
Author(s): Hillenbrand E E, Neville A M, Coventry B J
Primary Institution: Department of Surgery, University of Adelaide, Royal Adelaide Hospital
Hypothesis
The presence of CD1a-positive cells in breast tumors is associated with improved prognosis.
Conclusion
The study found that CD1a-positive cells are present in higher numbers in breast tumors compared to normal breast tissue.
Supporting Evidence
- The presence of CD1a+ cells was significantly higher in breast tumors than in normal tissue.
- Only two out of nine normal breast tissue cases expressed CD1a+ cells.
- CD1a+ cells were closely associated with tumor cells.
Takeaway
This study looked at special cells in breast tumors that might help the body fight cancer better.
Methodology
The study used immunohistochemistry to identify CD1a-positive cells in breast tumor samples.
Statistical Information
P-Value
0.0192
Statistical Significance
p=0.0192
Digital Object Identifier (DOI)
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