Acute Encephalitis Caused by Intrafamilial Transmission of Enterovirus 71 in Adult
2008

Adult Encephalitis from Enterovirus 71 Transmission

Sample size: 4 publication Evidence: low

Author Information

Author(s): Hamaguchi Tsuyoshi, Fujisawa Hironori, Sakai Kenji, Okino Soichi, Kurosaki Naoko, Nishimura Yorihiro, Shimizu Hiroyuki, Yamada Masahito

Primary Institution: Kanazawa University Graduate School of Medical Science

Hypothesis

Can Enterovirus 71 cause encephalitis in adults through intrafamilial transmission?

Conclusion

The case illustrates that Enterovirus 71 can cause severe encephalitis in adults, not just in children.

Supporting Evidence

  • Enterovirus 71 is typically associated with mild illness in adults.
  • The mother showed symptoms similar to those of children with EV71 encephalitis.
  • All three children recovered from hand, foot, and mouth disease without complications.
  • Genetic analysis confirmed intrafamilial transmission of the virus.

Takeaway

This study shows that adults can get really sick from a virus that usually affects kids, and it can spread in families.

Methodology

Case report detailing clinical symptoms, laboratory tests, and genetic analysis of virus isolates.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

A 37-year-old woman and her three sons aged 1, 5, and 7.

Digital Object Identifier (DOI)

10.3201/eid1405.071121

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