Effect of Carbon Dioxide Laser Ablation Followed by Intralesional Steroids on Keloids
2011

Effect of CO2 Laser and Steroids on Keloids

Sample size: 28 publication Evidence: moderate

Author Information

Author(s): Gaurav A Garg, Prajct P Sao, Uday S Khopkar

Primary Institution: Seth GS Medical College and KEM Hospital, Mumbai, India

Hypothesis

Does CO2 laser ablation followed by intralesional steroids reduce keloid recurrence?

Conclusion

CO2 laser followed by intralesional steroids is an effective treatment for keloids, but patients must be monitored for recurrence.

Supporting Evidence

  • Regular follow-up and steroid treatment led to no recurrence in 11 patients.
  • Only 2 out of 13 regular patients showed recurrence after 6 months.
  • Irregular patients had a higher recurrence rate, with 5 out of 10 showing 100% recurrence.

Takeaway

Doctors used a laser and steroids to treat bumps on the skin called keloids, and it worked better when patients followed the treatment plan.

Methodology

28 patients with 35 keloids were treated with CO2 laser and intralesional steroids over 6 months, with follow-ups to assess recurrence.

Potential Biases

Potential bias due to lack of randomization and control group.

Limitations

The study lacked a control group for comparison.

Participant Demographics

19 males and 9 females, aged 12 years and older.

Statistical Information

P-Value

0.0008976

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.4103/0974-2077.79176

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