Development of the retinotectal system in the direct-developing frog Eleutherodactylus coqui in comparison with other anurans
2008

Development of the Retinotectal System in Eleutherodactylus coqui

publication Evidence: moderate

Author Information

Author(s): Gerhard Schlosser

Primary Institution: Brain Research Institute, University of Bremen

Hypothesis

How does the differentiation of the retina in E. coqui relate to the differentiation of the optic tectum and other parts of the brain?

Conclusion

The study reveals that while growth in the retina and tectum of E. coqui is accelerated, their differentiation remains temporally coordinated with each other.

Supporting Evidence

  • E. coqui develops without a free-living larval stage, leading to precocious development of adult structures.
  • The retina and tectum in E. coqui grow rapidly during embryonic stages, reaching near adult size at hatching.
  • Differentiation of the retina and tectum remains coordinated despite accelerated growth.

Takeaway

This study looks at how a frog that skips the tadpole stage develops its eyes and brain. It finds that while the eyes grow quickly, they still develop in a way that is connected to the brain.

Methodology

The study compares growth and differentiation of the retina and tectum in E. coqui with other frogs using morphometry, immunohistochemistry, and in situ hybridization.

Digital Object Identifier (DOI)

10.1186/1742-9994-5-9

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication