Clade 2.3.2 Avian Influenza Virus (H5N1), Qinghai Lake Region, China, 2009–2010
2011
Clade 2.3.2 Avian Influenza Virus (H5N1) in China
Sample size: 11
publication
Evidence: moderate
Author Information
Author(s): Hu Xudong, Liu Di, Wang Mingyang, Yang Le, Wang Ming, Zhu Qingyu, Li Laixing, Gao George F.
Primary Institution: China Agricultural University College of Veterinary Medicine
Hypothesis
How did the H5N1 avian influenza virus evolve and spread in the Qinghai Lake region?
Conclusion
The study found that H5N1 viruses in the Qinghai Lake region changed from clade 2.2 to clade 2.3.2 and are likely transmitted by migratory birds.
Supporting Evidence
- Highly pathogenic avian influenza (H5N1) was first identified in migratory birds in 2005.
- Phylogenetic analysis showed that the H5N1 viruses isolated in 2009 and 2010 clustered as clade 2.3.2.
- Viruses from the Qinghai Lake region are closely related to those isolated in Mongolia and Uvs Nuur Lake.
Takeaway
Birds can spread a type of flu virus called H5N1, and scientists found that this virus changed over time in a specific area in China.
Methodology
Phylogenetic analysis and viral isolation from dead migratory birds.
Limitations
Surveillance data for wild animals near Qinghai Lake are limited.
Digital Object Identifier (DOI)
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