Study of Liver Diseases and Viral Genotypes in Colombia
Author Information
Author(s): Cortes-Mancera Fabian, Loureiro Carmen Luisa, Hoyos Sergio, Restrepo Juan-Carlos, Correa Gonzalo, Jaramillo Sergio, Norder Helene, Pujol Flor Helene, Navas Maria-Cristina
Primary Institution: Grupo de Gastrohepatología, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia
Hypothesis
What are the main risk factors and viral genotypes associated with end-stage liver diseases in Colombian patients?
Conclusion
The study found that alcohol consumption is the most common risk factor for end-stage liver diseases in Colombia, with HBV and HCV infections being less prevalent.
Supporting Evidence
- 71% of patients were diagnosed with cirrhosis.
- 12.2% were diagnosed with hepatocellular carcinoma (HCC).
- Alcohol consumption was the most frequent risk factor at 37.4%.
- Viral etiology accounted for only 17.6% of cases.
Takeaway
This study looked at people in Colombia with serious liver problems and found that drinking alcohol was a bigger problem than viruses like hepatitis B and C.
Methodology
The study involved a prospective analysis of 131 patients with end-stage liver diseases, collecting blood and liver tissue samples for viral characterization.
Limitations
The study's descriptive design and limited sample size do not allow for strong statistical associations to be made.
Participant Demographics
The mean age of participants was 58.1 years, with 65.6% being male.
Digital Object Identifier (DOI)
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