Serum procalcitonin level and leukocyte antisedimentation rate as early predictors of respiratory dysfunction after oesophageal tumour resection
2006

Predicting Breathing Problems After Esophageal Surgery

Sample size: 33 publication Evidence: moderate

Author Information

Author(s): Bogar Lajos, Molnar Zsolt, Tarsoly Piroska, Kenyeres Peter, Marton Sandor

Primary Institution: Department of Anaesthesiology and Intensive Care, University of Pecs, Hungary

Hypothesis

Can systemic inflammatory markers predict arterial hypoxaemia after oesophageal tumour resection?

Conclusion

An elevated leukocyte antisedimentation rate and procalcitonin concentration can predict next-day breathing problems after esophageal surgery.

Supporting Evidence

  • 17 out of 33 patients were classified as hypoxaemic after surgery.
  • Procalcitonin and LAR values at T2 were significantly predictive of hypoxaemia at T3.
  • The area under the ROC curve for LAR at T2 was 0.89, indicating strong predictive power.

Takeaway

Doctors can check certain blood markers after esophageal surgery to see if a patient might have trouble breathing the next day.

Methodology

A prospective observational study measuring inflammatory markers in patients after esophageal surgery.

Limitations

Short observation period, small sample size, and possible inaccuracies in temperature measurement.

Participant Demographics

33 consecutive patients undergoing elective oesophageal tumour resection.

Statistical Information

P-Value

p<0.001

Confidence Interval

95% CI, 0.77–1.00

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.1186/cc4992

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