Re-searcher: a system for recurrent detection of homologous protein sequences
2008

Re-searcher: A Tool for Finding Similar Protein Sequences

publication Evidence: moderate

Author Information

Author(s): Valdemaras Repšys, Mindaugas Margelevičius, Česlovas Venclovas

Primary Institution: Institute of Biotechnology, Vilnius University

Hypothesis

Re-searcher aims to provide a highly configurable environment for recurrent sequence searches to detect new homologs in protein databases.

Conclusion

Re-searcher allows for automatic periodic detection of both close and distant homologs with a user-friendly interface.

Supporting Evidence

  • Re-searcher is designed to handle multiple queries and provide results for each user.
  • The system can perform combined searches using profiles generated from previous searches.
  • It supports both local and remote database searches, enhancing flexibility.

Takeaway

Re-searcher is a computer program that helps scientists find similar proteins by checking databases regularly and telling them when new ones are found.

Methodology

Re-searcher uses PSI-BLAST for sequence searches and can be configured for local or remote database searches.

Digital Object Identifier (DOI)

10.1186/1471-2105-9-296

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