The Role of Macronutrients and Gut Microbiota in Neuroinflammation Post-Traumatic Brain Injury: A Narrative Review
2024

The Role of Macronutrients and Gut Microbiota in Neuroinflammation Post-Traumatic Brain Injury

publication Evidence: moderate

Author Information

Author(s): Antonella Cotoia, Ioannis Alexandros Charitos, Alberto Corriero, Stefania Tamburrano, Gilda Cinnella

Primary Institution: Department of Intensive Care, University Hospital of Foggia, Italy

Hypothesis

Can dietary macronutrients and gut microbiota influence neuroinflammation and recovery after traumatic brain injury?

Conclusion

Dietary strategies targeting gut health may help reduce neuroinflammation and support recovery after traumatic brain injury.

Supporting Evidence

  • Specific macronutrients can influence gut microbiota composition and modulate neuroinflammation.
  • Dysregulation of the gut-brain axis is a critical factor in the neuroinflammatory response.
  • Targeted nutrition and gut health optimization could serve as promising therapeutic modalities in TBI management.

Takeaway

Eating the right foods can help your brain heal after an injury by keeping your gut healthy.

Methodology

This narrative review synthesizes preclinical and clinical evidence regarding the impact of dietary macronutrients and gut microbiota on neuroinflammation following traumatic brain injury.

Limitations

The review highlights gaps in clinical research and the need for well-designed trials to establish efficacy and safety of dietary interventions.

Digital Object Identifier (DOI)

10.3390/nu16244359

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication