Synergistic Effects of Traffic-Related Air Pollution and Exposure to Violence on Urban Asthma Etiology
2007

Traffic Pollution and Urban Asthma: The Role of Violence Exposure

Sample size: 413 publication 10 minutes Evidence: moderate

Author Information

Author(s): Jane E. Clougherty, Jonathan I. Levy, Laura D. Kubzansky, P. Barry Ryan, Shakira Franco Suglia, Marina Canner, Rosalind J. Wright

Primary Institution: Harvard School of Public Health

Hypothesis

Does exposure to violence modify the effects of traffic-related air pollution on childhood asthma development?

Conclusion

The study found that traffic-related air pollution is associated with asthma in urban children who have been exposed to violence.

Supporting Evidence

  • Children with above-median exposure to violence showed a significant association between traffic-related pollution and asthma.
  • The odds ratio for asthma diagnosis increased with higher nitrogen dioxide levels among children exposed to violence.
  • Chronic stress from violence may enhance susceptibility to the effects of air pollution.

Takeaway

Kids living in areas with a lot of traffic pollution and who see violence are more likely to have asthma.

Methodology

The study used GIS-based models to estimate traffic-related pollution exposure and merged this data with questionnaire responses on violence exposure.

Potential Biases

Recall bias may affect the reporting of violence exposure and asthma diagnosis.

Limitations

The sample size was small for investigating multiplicative effects, and there was potential misclassification of exposure due to residential instability.

Participant Demographics

Participants were children from lower-income urban communities in East Boston, with a significant portion exposed to violence.

Statistical Information

P-Value

0.03

Confidence Interval

95% CI, 1.14–2.33

Statistical Significance

p = 0.03

Digital Object Identifier (DOI)

10.1289/ehp.9863

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