Femoral venous oxygen saturation is no surrogate for central venous oxygen saturation
2011

Femoral venous oxygen saturation vs. central venous oxygen saturation

Sample size: 130 publication Evidence: moderate

Author Information

Author(s): Van der Schors A, Van Beest P, Liefers H, Coenen L, Braam R, Spronk P

Primary Institution: Gelre Hospitals, Apeldoorn, the Netherlands

Hypothesis

Can femoral venous oxygen saturation (SfvO2) be used interchangeably with central venous oxygen saturation (ScvO2)?

Conclusion

Femoral venous oxygen saturation is not a suitable surrogate for central venous oxygen saturation.

Supporting Evidence

  • ScvO2 and SfvO2 correlated significantly in the control group.
  • Mean values of SfvO2 and ScvO2 were similar in surgical patients at T = 0.
  • Bland-Altman analysis showed large limits of agreement between ScvO2 and SfvO2.

Takeaway

The study found that measuring oxygen levels in the femoral vein doesn't give the same information as measuring it in the central vein, so they can't be used the same way.

Methodology

A single-center, prospective, controlled, observational study was conducted with 100 stable cardiac patients as a control group and 30 high-risk surgical patients.

Limitations

The study was conducted at a single center and involved a limited number of patients.

Participant Demographics

Stable cardiac patients undergoing elective right heart catheterization and high-risk surgical patients.

Statistical Information

P-Value

P < 0.0001

Confidence Interval

95% CI = 0.50 to 0.80

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/cc9460

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