Prevalence of Helicobacter pylori in HIV-infected Ugandan children
Author Information
Author(s): Hestvik Elin, Tylleskar Thorkild, Ndeezi Grace, Grahnquist Lena, Olafsdottir Edda, Tumwine James K, Kaddu-Mulindwa Deogratias H
Primary Institution: Centre for International Health, University of Bergen
Hypothesis
What is the prevalence of Helicobacter pylori colonization in HIV-infected, HAART-naïve Ugandan children?
Conclusion
HIV-infected, HAART-naïve Ugandan children had a lower prevalence of H. pylori colonization compared with healthy Ugandan children.
Supporting Evidence
- The overall prevalence of H. pylori in the HIV-infected children was 22.5%.
- Children with a low CD4 cell percentage had a lower risk of H. pylori colonization.
- The prevalence of H. pylori was lower in HIV-infected children compared to healthy children in the same area.
Takeaway
The study found that kids in Uganda with HIV are less likely to have a stomach bug called H. pylori compared to healthy kids.
Methodology
A hospital-based survey tested 236 HIV-infected children for H. pylori using a faecal antigen test and collected socio-demographic data.
Limitations
The study had a small number of older children and lacked data on the specificity and sensitivity of the test in HIV-infected populations.
Participant Demographics
Children aged 0-12 years, with a mean age of 2.9 years, including 121 girls and 115 boys.
Statistical Information
P-Value
0.002
Confidence Interval
95%
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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