Roles of LncRNAs and CircRNAs in Pulpitis
Author Information
Author(s): Fuchen-Ramos Dulce Martha, Leija-Montoya Ana Gabriela, González-Ramírez Javier, Isiordia-Espinoza Mario, García-Arévalo Fernando, Pitones-Rubio Viviana, Olvera-Sandoval Carlos, Mateos-Corral Isis, Serafín-Higuera Nicolás
Primary Institution: Facultad de Odontología Mexicali, Universidad Autónoma de Baja California
Hypothesis
This review aims to analyze the biological role of lncRNAs and circRNAs in pulpitis and discuss new research prospects.
Conclusion
LncRNAs and circRNAs are key regulators in pulpitis, influencing various biological processes such as inflammation and immune response.
Supporting Evidence
- LncRNAs and circRNAs are involved in various biological functions in pulpitis, including apoptosis and inflammation.
- Experimental studies show that lncRNAs can modulate immune responses in pulpitis.
- CircRNAs have been shown to regulate inflammatory pathways in pulpitis models.
- Emerging evidence suggests that lncRNAs and circRNAs could serve as potential biomarkers for pulpitis.
Takeaway
This study looks at how certain RNA molecules help control inflammation in tooth pulp infections.
Methodology
A literature search was performed using databases like PUBMED, SCOPUS, and Web of Science, focusing on lncRNAs and circRNAs in pulpitis.
Limitations
The review primarily focuses on in silico analyses and lacks experimental validation for many findings.
Digital Object Identifier (DOI)
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