Physical activity and risk of colon adenoma: a meta-analysis
2011

Physical Activity and Colon Adenoma

Sample size: 20 publication 10 minutes Evidence: moderate

Author Information

Author(s): Wolin K Y, Yan Y, Colditz G A

Primary Institution: Washington University School of Medicine in St Louis

Hypothesis

What is the relationship between physical activity and the risk of colon adenomas?

Conclusion

Physical activity is significantly associated with a reduced risk of colon adenomas, suggesting it plays an important role in colon cancer prevention.

Supporting Evidence

  • The overall relative risk of colon adenomas associated with physical activity was 0.84.
  • The association was significant for both men and women.
  • Physical activity was associated with a stronger effect on large or advanced adenomas.

Takeaway

Being active can help keep your colon healthy and lower the chances of getting certain types of growths that can lead to cancer.

Methodology

A systematic literature review and meta-analysis of 20 studies examining physical activity and colon adenoma risk.

Potential Biases

Potential publication bias was assessed using funnel plots.

Limitations

The studies included varied in their definitions of physical activity and case definitions.

Participant Demographics

Studies included both men and women, with varying sample sizes.

Statistical Information

P-Value

0.16

Confidence Interval

0.77–0.92

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1038/sj.bjc.6606045

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