No Link Between Anti-Phospholipid Antibodies and ADHD in Kids
Author Information
Author(s): SHAY BUJANOVER, YAIR LEVY, MIRIAM KATZ, YAEL LEITNER, ISAAC VINOGRAD, YEHUDA SHOENFELD
Primary Institution: Chaim Sheba Medical Center
Hypothesis
Does the presence of anti-phospholipid antibodies (APLA) contribute to the development of Attention Deficit/Hyperactivity Disorder (ADHD) in children?
Conclusion
The study found no significant difference in anti-phospholipid antibody levels between children with ADHD and healthy controls.
Supporting Evidence
- The study included 70 children, with 41 diagnosed with ADHD and 29 healthy controls.
- Blood samples were screened for various anti-phospholipid antibodies using ELISA.
- The results showed no significant difference in antibody levels between the two groups.
Takeaway
The study looked at kids with ADHD and found that they don't have more of a certain type of antibody in their blood compared to kids without ADHD.
Methodology
The study compared blood samples from 41 children with ADHD to 28 healthy controls, testing for various anti-phospholipid antibodies using ELISA.
Potential Biases
Potential bias in self-reported family history of ADHD and autoimmune diseases.
Limitations
The study's sample size was relatively small and may not represent the broader population.
Participant Demographics
41 children with ADHD (90.2% male, age range 5-15) and 29 healthy controls (75.9% male, age range 4-13).
Statistical Information
P-Value
0.001
Statistical Significance
p=0.001
Digital Object Identifier (DOI)
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