Comparative meta-analysis of cold snare polypectomy and endoscopic mucosal resection for colorectal polyps: assessing efficacy and safety
2024

Comparing Cold Snare Polypectomy and Endoscopic Mucosal Resection for Colorectal Polyps

Sample size: 15296 publication 10 minutes Evidence: moderate

Author Information

Author(s): Wang Shouqi, Zhang Qi, Meng Li Rong, Wu Ying, Fong Pedro, Zhou Weixia

Primary Institution: The Second Affiliated Hospital, Soochow University, Soochow, China

Hypothesis

This meta-analysis aimed to compare the efficacy and safety of cold snare polypectomy (CSP) and endoscopic mucosal resection (EMR) in the management of colorectal polyps.

Conclusion

CSP is a safe, efficient, and effective technique comparable to EMR, with a lower delayed bleeding rate but a lower complete resection rate.

Supporting Evidence

  • CSP had a significantly lower complete resection rate compared to EMR.
  • CSP had a significantly lower delayed bleeding rate compared to EMR.
  • There was no significant difference in en bloc resection rate between CSP and EMR.
  • The procedure time was similar between CSP and EMR.

Takeaway

Doctors can use two methods to remove polyps from the colon: cold snare polypectomy (CSP) and endoscopic mucosal resection (EMR). CSP is safer and causes less bleeding, but EMR works better for completely removing polyps.

Methodology

A meta-analysis was conducted using data from six studies involving 15,296 patients, comparing the outcomes of CSP and EMR.

Potential Biases

Some studies had unclear risks in randomization and reporting, which may affect the reliability of the results.

Limitations

The study did not include data on recurrence rates after CSP and EMR, and lacked a cost-effectiveness analysis.

Participant Demographics

Patients included in the studies ranged from 51.6 to 72 years old, with a male representation of 55% to 78.3%.

Statistical Information

P-Value

0.0334

Confidence Interval

[0.21–0.94]

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.7717/peerj.18757

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