The Role of Maternal and Early-Life Diet in Inflammatory Bowel Disease
2024
The Role of Maternal and Early-Life Diet in Inflammatory Bowel Disease
Sample size: 23
publication
Evidence: moderate
Author Information
Author(s): Karaivazoglou Katerina, Triantos Christos, Aggeletopoulou Ioanna
Primary Institution: University Hospital of Patras
Hypothesis
Maternal and early-life diet may be associated with intestinal inflammation and colitis severity.
Conclusion
Dietary factors during pregnancy and early life are involved in IBD pathogenesis, with potential for both exacerbating and protective effects.
Supporting Evidence
- High-fat and high-protein diets during gestation and neonatal life induce gut dysbiosis and amplify intestinal inflammation.
- Maternal diet quality, including fish and vegetable intake, significantly decreased IBD risk.
- Certain dietary bioactive compounds may protect against colonic inflammation.
Takeaway
What moms eat while pregnant and what babies eat early in life can affect their chances of getting a tummy disease called IBD.
Methodology
A thorough literature search was performed across Pubmed and ScienceDirect, including both human and animal studies.
Limitations
Human data are limited and need larger investigations for clarity.
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website