Individual Pharmacotherapy Management (IPM-II) for Patient and Drug Safety in Polypharmacy via Clinical Electronic Health Record Is Associated with Significant Fall Prevention
2024

Medication Management to Prevent Falls in Elderly Patients

Sample size: 404 publication 10 minutes Evidence: high

Author Information

Author(s): Wolf Ursula, Drewas Luise, Ghadir Hassan, Bauer Christian, Becherer Lars, Delank Karl-Stefan, Neef RĂ¼diger

Primary Institution: University Hospital Halle (Saale), Martin Luther University Halle-Wittenberg

Hypothesis

Can Individual Pharmacotherapy Management (IPM) reduce in-hospital falls among elderly patients on polypharmacy?

Conclusion

The study found that IPM significantly reduced in-hospital falls in elderly patients from 9% to 1.5%.

Supporting Evidence

  • IPM was associated with a significant reduction in in-hospital falls.
  • The number needed to treat to prevent one fall was 14.
  • Baseline characteristics were similar between the control and intervention groups.
  • IPM adjusted medications based on individual patient needs.
  • Factors associated with falls included antipsychotics and cognitive impairment.

Takeaway

This study shows that adjusting medications for older patients can help prevent falls in the hospital.

Methodology

A retrospective pre-post intervention study comparing 200 patients before IPM implementation with 204 patients during the IPM intervention.

Potential Biases

The study population mainly consisted of patients with a history of falls, which may predispose them to re-fall.

Limitations

The study is retrospective, which may introduce bias, and it did not account for all potential confounding factors.

Participant Demographics

Elderly patients, predominantly female, aged 70 and older.

Statistical Information

P-Value

0.021

Confidence Interval

[95% CI 0.04; 0.76]

Statistical Significance

p = 0.021

Digital Object Identifier (DOI)

10.3390/ph17121587

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