Global dissemination of a single mutation conferring white pericarp in rice
2007

Spread of a Mutation for White Rice

Sample size: 440 publication 10 minutes Evidence: high

Author Information

Author(s): Sweeney Megan T, Thomson Michael J, Cho Yong Gu, Park Yong Jin, Williamson Scott H, Bustamante Carlos D, McCouch Susan R

Primary Institution: Cornell University

Hypothesis

The study investigates the origin and dissemination of a mutation that causes white pericarp in rice.

Conclusion

The 14-bp deletion mutation responsible for white pericarp in rice is found in 97.9% of white rice varieties and originated in the japonica subspecies.

Supporting Evidence

  • The 14-bp deletion in the Rc gene is present in 97.9% of white rice varieties surveyed.
  • The mutation originated in the japonica subspecies and was introgressed into indica varieties.
  • Strong positive selection for the white allele was observed during rice domestication.

Takeaway

Scientists found that a small change in rice genes made most rice white instead of red, and this change spread widely because people liked the white rice.

Methodology

The study involved genotyping 440 rice cultivars from diverse geographic and genetic backgrounds to identify the presence of the 14-bp deletion in the Rc gene.

Potential Biases

Potential bias in the selection of rice varieties may affect the generalizability of the findings.

Limitations

The study may not account for all genetic variations affecting pericarp color in rice.

Participant Demographics

The study included rice varieties from 24 different countries across three continents.

Statistical Information

P-Value

p<0.05

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pgen.0030133

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