(E)-2-Methyl-6-[(1-phenyl-1H-pyrazol-4-yl)methylidene]cyclohexanone C17H18N2O
2011
New Heterocyclic Compound from Aldehyde and Cyclohexanone
publication
Evidence: moderate
Author Information
Author(s): Asiri Abdullah M., Faidallah Hassan M., Ng Seik Weng
Primary Institution: King Abdul Aziz University
Hypothesis
The compound derived from 1-phenylpyrazole-4-carboxaldehyde and 2-methylcyclohexanone is expected to possess useful biological activity.
Conclusion
The study successfully synthesized a new heterocyclic compound with a specific crystal structure.
Supporting Evidence
- The compound has two independent molecules with a flattened chair conformation.
- The phenyl and pyrazole rings are approximately coplanar.
- Weak intermolecular hydrogen bonding is present in the crystal structure.
Takeaway
Scientists made a new chemical by mixing two other chemicals, and they found that it has a special structure that might be helpful for medicine.
Methodology
The compound was synthesized by reacting 1-phenylpyrazole-4-carboxaldehyde with 2-methylcyclohexanone in ethanol with potassium hydroxide.
Digital Object Identifier (DOI)
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