Cutaneous zosteriform endometrial cancer metastasis
2025

Skin Metastasis from Endometrial Cancer

Sample size: 1 publication Evidence: low

Author Information

Author(s): Wangxiang Luo, Xianhong Yang, Ren Yunlin, Tao Xiaohua, Lu Wei

Primary Institution: Zhejiang Provincial People's Hospital

Conclusion

The case highlights the rarity of cutaneous metastasis from endometrial cancer and the need for awareness of skin lesions in patients with a history of this cancer.

Supporting Evidence

  • The patient had a history of poorly differentiated endometrial cancer for 11 years.
  • Skin metastasis from carcinoma is rare, occurring in 0.7%–9% of metastatic cases.
  • Zosteriform metastasis is even rarer in endometrial cancer, with an incidence of less than 0.8%.
  • The patient presented with new skin lesions that were initially misdiagnosed as shingles.

Takeaway

A woman with endometrial cancer developed unusual skin bumps that turned out to be cancer spreading to her skin, which is very rare.

Methodology

The patient underwent a biopsy and immunohistochemistry to confirm the diagnosis of cutaneous metastasis.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

A 58-year-old woman with a history of poorly differentiated endometrial cancer.

Digital Object Identifier (DOI)

10.1111/1346-8138.17536

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