Geohelminth Infections among Pregnant Women in Rural Western Kenya; a Cross-Sectional Study
2009

Geohelminth Infections among Pregnant Women in Rural Western Kenya

Sample size: 390 publication 10 minutes Evidence: moderate

Author Information

Author(s): van Eijk Anna M., Lindblade Kim A., Odhiambo Frank, Peterson Elizabeth, Rosen Daniel H., Karanja Diana, Ayisi John G., Shi Ya Ping, Adazu Kubaje, Slutsker Laurence

Primary Institution: Kenya Medical Research Institute

Hypothesis

What are the prevalence and effects of geohelminth infections among pregnant women in rural western Kenya?

Conclusion

Geohelminth infections are common in this pregnant population; however, there were few observed detrimental effects.

Supporting Evidence

  • 76.2% of participants were infected with at least one geohelminth.
  • A. lumbricoides was the most prevalent infection at 52.3%.
  • Hookworm infections were associated with lower hemoglobin levels.
  • Women with A. lumbricoides were less likely to have malaria parasitemia.
  • Geohelminth infections were not associated with clinical symptoms.

Takeaway

Many pregnant women in rural Kenya have infections from worms, but these infections don't seem to make them very sick.

Methodology

Pregnant women were interviewed and provided blood and stool samples to identify geohelminth infections.

Potential Biases

Participants who did not provide stool samples were more likely to use unprotected water sources, which may bias the results.

Limitations

The study had a small sample size and used a single stool specimen to assess infection status.

Participant Demographics

The majority of participants were of Luo ethnicity, with a median age of 25 years.

Statistical Information

P-Value

0.009

Confidence Interval

95% CI 1.1–3.0

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1371/journal.pntd.0000370

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