3′-(3-Hydroxyphenyl)-4-methylspiro[benzo[e][1,4]diazepine-3,2′-oxirane]-2,5(1H,4H)-dione
2011
Crystal Structure of a Benzodiazepine Metabolite
publication
Evidence: high
Author Information
Author(s): Liu Jun-Liang, Hu Zhi-Yu, Xu Qing-Yan
Primary Institution: Xiamen University
Conclusion
The study successfully determined the crystal structure of the compound, revealing its unique conformation and hydrogen bonding interactions.
Supporting Evidence
- The compound's structure was confirmed through X-ray crystallography.
- The seven-membered ring of the compound adopts a boat conformation.
- Hydrogen bonding interactions stabilize the crystal packing.
Takeaway
Scientists figured out the structure of a special chemical made by a type of fungus, which helps us understand how it works.
Methodology
The compound was extracted from a cultured fungus and purified through various chromatography techniques before structural analysis.
Digital Object Identifier (DOI)
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